Dr. Dionysios Veronikis, Vaginal Surgery and Urogynecology, St. Louis, MO

Improve Safety & Efficacy of Pelvic Floor Surgery

Traditional surgical approaches to pelvic organ prolapse (POP) and associated stress urinary incontinence can fall short of desired outcomes.

  • Native tissue repairs vary in durability and may require re-operation. The scarring caused by these procedures may lead to direct or referred pain and impaired urinary, bowel or sexual function.
  • Synthetic mesh implants have been implicated in a significant number of complications, such as pain and bleeding from exposure of the mesh in the vagina and erosions into the bladder or bowel. Further, the data on whether mesh-augmented surgery is superior to native tissue repairs are variable. 1

A 2016 Cochrane review found, “The use of mesh for anterior prolapse was associated with an increased risk of any repeat surgery, which was driven by surgery for mesh removal. Native tissue and vaginal mesh surgery had similar 5-year risks for surgery for recurrent prolapse.” 2

A Better Solution

ARMS Medical has pioneered an exceptional approach to pelvic floor surgery based on the use of a next-generation biologic:

DermaPure® decellularized dermal allograft featuring patented dCELL® technology. This intact extracellular matrix is intended for supplemental support, protection and reinforcement for soft tissue repair.

Our product suite also includes the following curated surgical tools:

  • StitchKit® suturing technology for robotically assisted repair of pelvic organ prolapse
  • Smoke Evacuation Pencil for removal of smoke and liquid during electrocauterization
  • Veronikis Vaginal Retractor System™ for vaginal surgery

Novel Biologic

A recent review of surgical updates for the treatment of POP noted:

Some investigators are looking for novel graft materials derived from the extracellular matrix that can be inserted at the time of prolapse repair to promote site-specific functional tissue remodeling without the risk of erosion. 3

DermaPure® tissue allograft is the cleanest and most pristine extracellular matrix available. The dCELL process removes cellular and DNA material from biological tissues, leaving an intact scaffold for regeneration and repopulation of the patient’s cells.

Competitive technologies leave residual DNA, can damage collagen structures and do not hold up long enough for permanent vasculature and cell development. In contrast, the dCELL process delivers a “clean slate” with the long-term strength required for full regeneration.

Once cell repopulation and blood vessel replacement are complete, the graft is effectively a natural part of the patient’s own tissue.

Download DermaPure® brochure (PDF)

When they removed the mesh, the Dermapure® was deployed to completely re-construct my urethra. It’s as if this product also fixed not just the damage mesh had created in my body but also retro repaired what childbirth had done to my urethra and my bladder. It’s truly been a miracle…I wish for more women to be able to experience the amazing recovery that I’ve enjoyed and I am grateful there are companies out there like ARMS that create products like Dermapure® so women like me can participate in our lives uninhibited and unencumbered by a medical condition.

— Christine V., Patient and Registered Nurse

Advantages for the Surgeon

  • Flexibility: Suitable for both abdominal and trans-vaginal surgery, including robotic surgery.
  • Optimal recovery speed: Higher quantity/quality of vascularization in 21 days with full integration by 6-8 weeks post-operative.
  • Minimized scarring: Controls negative immunogenic and inflammatory responses
  • Safety: Avoids the use of synthetic mesh.
  • Ease of use: Optimizes graft handling and high suture pullout strength.